Progrp and gastrin
WebProgastrin-releasing peptide (proGRP) is produced in about two-thirds of SCLC tumors and is used as a specific marker for SCLC. Although GRP is known to have a variety of … WebAug 4, 2014 · To determine the expression and biology of the neuroendocrine growth factor gastrin-releasing peptide (GRP) and other proGRP-derived peptides in renal cancer. …
Progrp and gastrin
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WebApr 1, 1994 · Gastrin-releasing peptide (GRP) is a specific and an actively secreted product of small cell lung carcinoma (SCLC) cells. Based on this observation, we attempted to develop a new approach for early detection of SCLC and for monitoring therapeutic response in SCLC patients. WebPro-Gastrin-Releasing-Peptide, also known as Pro-GRP, is a Gastrin-Releasing-Peptide (GRP) precursor, a neurotransmitter that belongs to the bombesine /neuromedin B …
WebJul 1, 2024 · Background: The diagnostic sensitivity and specificity of serum Pro-gastrin-releasing peptide (ProGRP) in benign or malignant diseases remains controversial. Methods: The clinical data of 6,948... WebProGRP, the precursor form of gastrin-releasing peptide (GRP), the mammalian counterpart of amphibian bombesin, is a useful tumor marker in SCLC. Abnormal ProGRP (>50 pg/mL) may be found only in a small subset of patients with benign (0.4%) or malignant disease (24%, 99% with concentrations <100 pg/mL), excluding SCLC and neuroendocrine tumors.
WebProGRP is a specific tumour marker for small cell lung cancer (SCLC), and it has advantages over other tumour markers in terms of tumour specificity, release amount, and organ specificity. The ...
WebBackground: To investigate the roles of gastrin-releasing peptide (ProGRP) in the diagnosis of small cell lung cancer (SCLC). Methods: We retrospectively analyzed data from 11,206 patients with clinical suspicion of lung cancer from January 1, 2015 to May 31, 2024. ProGRP and neuron-specific enolase (NSE) were detected in peripheral blood, and ...
WebJun 28, 2024 · Gastrin-releasing peptide (GRP) is the gastrointestinal hormone which has the effect on promoting secretion of gastrin, widely in normal human brains, nerve fibers … da-30d メンテナンスWebMay 1, 1996 · Comparing the area under curve (AUC) of 'receiver operator characteristics' of ProGRP(31-98) with that of NSE, ProGRP(31-98) was the more powerful marker in the diagnosis of SCLC (P = 0.0001). da 310usb アップコンバートWebJul 17, 2024 · CEA, carcinoembryonic antigen; NSE, neuron-specific enolase; ProGRP, pro-gastrin-releasing peptide precursor; SCLC, small cell lung cancer. Apparently, ProGRP and NSE are two of the tumor markers of SCLC that are preferentially used to diagnose diseases. Typically, the diagnostic specificity of NSE is rather limited owing to a relatively high ... da-30d/60s用メンテナンスキットWebJul 1, 2024 · ProGRP is a reliable tumor marker for the diagnosis of ESFTs and evaluation of treatment response. Introduction Ewing sarcoma (ES) is a highly malignant tumor composed of small round cells, as first described by Lücke in 1866 [ 1 ]. Over the last 40 years, the occurrence of histologically similar tumors has been reported. da310usb ドライバWebDec 1, 2011 · ProGRP is a precursor form of gastrin-releasing peptide (GRP) (or mammalian bombesin), which is a neuropeptide hormone originally isolated from porcine gastric tissue [9]. GRP is widely distributed throughout the gastrointestinal and pulmonary tract. GRP is produced by SCLC cells and could be helpful in the monitoring of patients [10]. da3600es アップデートWebApr 13, 2024 · However, plasma pro–gastrin-releasing peptide (ProGRP) became higher with disease progression, and SCLC was detected at the second biopsy. It is suggested that elevation of plasma ProGRP level before EGFR-TKI therapy is useful for predicting EGFR-mutant NSCLC to SCLC transformation. da350kaw再セットアップWebMar 29, 2024 · 胃释放肽前体（ProGRP），是GRP的前体，在血浆中能稳定存在，人ProGRP有三种剪接异构体，但羧基末端有一个共同序列区，即31-98片段。大量研究证实ProGRP水平能够代表GRP水平和GRP基因表达，是一种新的肿瘤标志物[3]。 2 临床意义是什 … da 310usb ライン出力