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Btg3 and p53

WebOther articles where TP53 is discussed: tumour suppressor gene: …tumour suppressor genes (such as TP53, which encodes a protein known as p53) have been identified. The mutated form of TP53 has been implicated in … WebNov 18, 2014 · When DNA is damaged, p53 is upregulated, which will induce DNA repair and cause the cell cycle arrest at G1/S-phase. If damage cannot be repaired, p53 will induce programmed cell death or apoptosis. It has been demonstrated that BTG2 exerts its antitumor effect through p53-dependent Ras signal transduction pathway . Thus, the …

绵羊胚胎发育中后期骨骼肌BTG2/3的表达动态及其与Myostatin的 …

WebApr 9, 2013 · B-cell translocation gene 3 (BTG3) is a member of the antiproliferative BTG/ Transducer of ErbB2 gene family and is induced by genotoxic stress in a p53- and Checkpoint kinase 1 (CHK1)-dependent manner. Down-regulation of BTG3 has been observed in human cancers, suggesting that it plays an important … WebSep 16, 2024 · B cell transposition gene 3 (BTG3) is reported to be a tumor suppressor and suppresses proliferation and cell cycle progression. This study aims to analyze the clinicopathological and prognostic significances, and signal pathways of BTG3 mRNA expression in human beings through bioinformatics analysis. We analyzed BTG3 … memorial day coloring sheets for preschoolers https://fkrohn.com

Candidate tumor suppressor BTG3 maintains genomic stability by …

Webp53 regulated genes curated by M. Fisher (Fischer M. Census and evaluation of p53 target genes. Oncogene. 2024; 36: 3943-3956. PMID: 28288132 ). All genes have been converted to mouse. Database was created by Angela Mak and Mark Knepper in the Epithelial Systems Biology Laboratory (Mark Knepper, Chief) at the National Heart, Lung and Blood ... WebDec 11, 2024 · B-cell translocation gene 3 (BTG3) is a member of the antiproliferative BTG gene family and is a downstream target of p53. Here, we show that senescence … Webbtg3在g1期表达量最高，g1-s期表现出峰值[16]。 BTG3表达缺失与肺癌的发生有关[17]，也能增强BMP诱导的骨形成[18]。 肌肉生长抑制素(Myostatin，MSTN) 基因是TGF-β超家族成员，是骨骼肌生长的负调控因子，为生长发育性状的候选基因。 memorial day coloring sheet

The candidate tumor suppressor BTG3 is a transcriptional …

Category:54971 - Gene ResultBANP BTG3 associated nuclear …

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Btg3 and p53

Down-regulation of BTG3 promotes cell proliferation

Webp53. Target Genes. Recent genome-wide analyses and meta-analyses of genome-wide datasets of p53 DNA-binding and gene regulation show that p53 is a direct activator of a limited number of genes compared to the number of putative response-elements identified genome-wide. They also provide evidence that p53 is not a direct repressor of genes . WeblncRNA MEG3、miR-373-5p引物均购自上海吉凯制药有限公司；Lipofectamine2000转染试剂购自重庆市华雅干细胞技术有限公司；DMEM培养基购自上海微科生物技术有限公司；牛血清、0.25%胰蛋白酶均购自上海素尔生物科技有限公司；鼠抗人BTG3单克隆抗体购自上海圻明生物科技 ...

Btg3 and p53

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WebMar 22, 2024 · The role of tumor suppressor p53 in metabolism and energy regulation, and its implication in cancer and lifestyle-related diseases. Endocr J. 2024;66(6):485-496. … WebOct 1, 2007 · BTG3 protein is induced by DNA damage in a p53-dependent manner. ( A ) BTG3 in LNCaP cells is induced by various DNA damage agents. Cells were treated with 8 Gy of X-ray (lanes 2–4), 0.5 mM of H ...

WebAug 9, 2007 · Proper regulation of cell cycle progression is pivotal for maintaining genome stability. In a search for DNA damage-inducible, CHK1-modulated genes, we have identified BTG3 (B-cell t ranslocation g ene 3) as a direct p53 target. The p53 transcription factor binds to a consensus sequence located in intron 2 of the gene both in vitro and in vivo, … WebWe have previously shown that BTG3 is transcriptionally activated by p53 upon genotoxic assault 16 . BTG3 binds E2F1 to control cell proliferation and the G2 checkpoint 16. Loss of Btg3 in mice ...

WebOct 17, 2013 · BTG3 is a downstream target of p53 and also binds and inhibits E2F1. It connects functionally those two major growth-regulatory pathways. BTG3 triggers acute cellular senescence via the ERK-JMJD3-p16 signaling axis. However, the expression pattern and functions of BTG3 in HCC remain unknown. In this study, we detected the … WebAbstract Exposure of mammalian cells to genotoxic agents evokes a complex cellular response. An ordered series of molecular events is necessary to sense DNA damage, …

WebAug 9, 2007 · Proper regulation of cell cycle progression is pivotal for maintaining genome stability. In a search for DNA damage-inducible, …

WebJan 27, 2016 · p53 deficiency leads to increased growth at metastatic sites. Tumor-bearing mice were monitored for signs of declining health and euthanized when they exhibited … memorial day colors to wearWebMar 1, 2000 · B-cell translocation gene 3 (BTG3), also known as ANA, TOB5, TOFA, APRO4, TOB55, and ANA/BTG3, belongs to the BTG gene family and plays its role as a downstream target of p53 [8] [9]. BTG3 has a ... memorial day colors officialWebFeb 1, 2000 · Exposure of mammalian cells to genotoxic agents evokes a complex cellular response. An ordered series of molecular events is necessary to sense DNA damage, transduce the signal, and ultimately delay the cell cycle or trigger apoptosis. Recently, we have shown that BTG2/TIS21 gene expression was induced in response to DNA damage … memorial day columbus msWebDec 4, 2024 · BTG3 is a direct downstream target of miR-106b-5p. BTG3 overexpression inhibited tumor growth of SW620 cells by suppressing proliferation and inducing … memorial day coloring sheets for kidsWebDownload scientific diagram BTG3 protein is induced by DNA damage in a p53-dependent manner. ( A ) BTG3 in LNCaP cells is induced by various DNA damage agents. Cells were treated with 8 Gy of X ... memorial day concert 2022 liveWebp53 is a transcription factor that activates many genes involved in essential maintenance of genetic stability. P53 is the most frequently mutated gene in human cancers. One-third of … memorial day colors wardrobeWebMar 29, 2024 · BANP BTG3 associated nuclear protein [ (human)] Gene ID: 54971, updated on 29-Mar-2024 Summary This gene encodes a protein that binds to matrix attachment … memorial day computer sales best buy